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Risks from vaccination against yellow fever - again Print E-mail
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พุธ, 26 พฤศจิกายน 2008

Lindsey NP, Schroeder BA, Miller ER, et al. Adverse event reports following
yellow fever vaccination. Vaccine. 2008; 26:6077-6082.


CONCLUSION: New data on adverse effects (AEs) of yellow fever (YF) vaccination
are reported from the Centers for Disease Control and Prevention (CDC). The
updated figures may be expressed roughly as: all-age AEs: 1 per 2,000
vaccinations; all-age serious adverse events (SAEs): 1 per  21,000; all-age
YF-vaccine associated neurotropic disease (YF-AND: 1 per 125,000 vaccinations;
all age yellow-fever vaccine-associated viscerotropic disease (YF-AVD): 1 per
250,000; age > 60 years YF-AND: 1 per 56,000 vaccinations; age > 60 years
YF-AVD: 1 per 71,000 vaccinations; and all-age serious anaphylactic reactions: 1
per 55,000 vaccinations. The risks of serious adverse events remain of serious
concern to travelers intending to go to countries where they may be at risk for
yellow fever. Travel health advisors should discuss carefully risk and benefit
of YF vaccination in these age groups.

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